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Research Scientist in Ophthalmology

End date 25 Sep 2020
Nottingham, Full time

Research Scientist in Ophthalmology

Exonate Ltd, Nottingham.

Salary. £22000-£27000

Exonate Ltd ( is a fast growing, dynamic pharmaceutical company focussing on translating discoveries in alternative splicing technology to therapeutics. Exonate Ltd wish to appoint a research scientist to provide 12 months maternity cover at its laboratories based at Medicity Nottingham to aid its drug development program in ophthalmology and to develop new therapeutics for age related macular degeneration and diabetic retinopathy based on targeting alternative splicing.  The position will help discover and develop new drugs to treat these diseases as part of a well funded program within the company.  We are looking for motivated, flexible enthusiastic scientists with experience in cell biology, basic molecular biology, protein extraction and quantification, or equivalent. A BSc in relevant subject and laboratory experience is required. The position will involve experience with different ophthalmic cell cultures (including retinal epithelial cells), cytotoxicity and protein expression studies (western blots, immunoprecipitation). The ability to work well within the team, deliver to deadlines, problem solve, identify new opportunities and maintain excellent records is critical. Additional generic skills we are looking for include maintenance of safety records, regulatory experience (e.g. HTA, GMO, COSHH), safety training, laboratory management, ordering systems and general laboratory planning.  Teamwork, pro-activeness, enthusiasm, and engagement are critical in this environment, so we are looking for individuals who can be proactive in contributing to problem solving, working within part of the team, and helping others as well as learning on the job.

The successful candidate will join a thriving, dynamic and expanding research team consisting of ten researchers. Exonate Ltd.’s laboratory research space is based in Medicity Nottingham. The team includes pre and postdoctoral researchers. The project will be supervised by Dr Jennifer Batson, Principal Scientist in the company, under the overall direction of Dr Ken McKechnie, Head of Biology. The work by Exonate focuses on regulation of alternative splicing and how this controls angiogenesis, and cell signalling. Good communication, team working and report writing skills are essential and maintaining clear records and developing standard operating procedures for the methodology is critical. Excellent presentation skills are required, and in a fast moving and dynamic environment the ability to clearly communicate is critical. This research area, which integrates translational and basic science is an extremely exciting one to join and we are looking for individuals who are bright, motivated, enthusiastic and who want to be able to help make breakthroughs in our understanding and treatment of disease states.  . The laboratories have excellent facilities for biochemistry, cell biology, pharmacology and molecular biology, and full training will be given.

Exonate started in 2013, and this is a good opportunity to join us in our journey at an exciting stage in its growth and to see how a pharmaceutical company can grow. A flexible approach will mean you will be able to see operations from the laboratory floor to the boardroom, meet investors and consultants, and experience the excitement of a dynamic company as it expands.

Applicants should contact, to discuss the position informally, or submit a CV directly to